Is glucose pattern of OGTT associated with late-onset gestational diabetes and adverse pregnant outcomes?

ABSTRACT:

Background

The heterogeneity of oral glucose tolerance test (OGTT) patterns during pregnancy remains unclear. This study aims to identify latent OGTT patterns in pregnant women and investigate the high-risk population for late-onset gestational diabetes mellitus (GDM).

Methods

This study including 17,723 participants was conducted from 2018 to 2021. Latent mixture modeling was used to identify subgroups. Modified Poisson regression was performed to explore the relationship between OGTT patterns and late-onset GDM or adverse perinatal outcomes.

Results

Three distinct glucose patterns, high, medium, and low glucose levels (HG, MG, and LG patterns) were identified. The HG pattern represented 28.5% of the participants and 5.5% of them developed late-onset GDM. A five-fold

SUBMITTER: Zhang E 

PROVIDER: S-EPMC10810615 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature