A comparison of single- and double-threshold ROC plots for mixture distributions.

ABSTRACT: The receiver operating characteristics (ROC) analysis is commonly used in clinical settings to check the performance of a single threshold for distinguishing population-wise bimodal-distributed test results. However, for population-wise three-modal distributed test results, a single threshold ROC (stROC) analysis showed poor discriminative performance. The purpose of this study is to use a double-threshold ROC analysis for the three-modal distributed test results to provide better discriminative performance than the stROC analysis. A double-threshold receiver operating characteristic plot (dtROC) is constructed by replacing the single threshold with a double threshold. The sensitivity and specificity coordinates are chosen to maximize sensitivity for a given specificity value. Besides a si

SUBMITTER: Ibrar F 

PROVIDER: S-EPMC10810648 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature