Major depressive disorder associated alterations in the effective connectivity of the face processing network: a systematic review.

ABSTRACT: Major depressive disorder (MDD) is marked by altered processing of emotional stimuli, including facial expressions. Recent neuroimaging research has attempted to investigate how these stimuli alter the directional interactions between brain regions in those with MDD; however, methodological heterogeneity has made identifying consistent effects difficult. To address this, we systematically examined studies investigating MDD-associated differences present in effective connectivity during the processing of emotional facial expressions. We searched five databases: PsycINFO, EMBASE, PubMed, Scopus, and Web of Science, using a preregistered protocol (registration number: CRD42021271586). Of the 510 unique studies screened, 17 met our inclusion criteria. These studies identified that compared wit

SUBMITTER: Jamieson AJ 

PROVIDER: S-EPMC10810788 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature