Bi- and Tri-specific antibodies in non-Hodgkin lymphoma: current data and perspectives.
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ABSTRACT:
SUBMITTER: Abou Dalle I
PROVIDER: S-EPMC10810854 | biostudies-literature | 2024 Jan
REPOSITORIES: biostudies-literature
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Bi- and Tri-specific antibodies in non-Hodgkin lymphoma: current data and perspectives.
Abou Dalle Iman I Dulery Remy R Moukalled Nour N Ricard Laure L Stocker Nicolas N El-Cheikh Jean J Mohty Mohamad M Bazarbachi Ali A
Blood cancer journal 20240125 1
Bispecific antibodies (BsAbs) are a new group of targeted therapies that are revolutionizing the treatment landscape of B-cell non-Hodgkin's lymphoma (B-NHL). In the relapsed/refractory setting, salvage chemotherapy and autologous stem cell transplantation are capable of curing 50% of patients, whereas the other half will have a dismal outcome with a median overall survival of less than 12 months. This unmet need reinforced the importance of innovative therapies like the BsAbs and CAR-T cell the ...[more]
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