Extent of Surgery for Medullary Thyroid Cancer and Prevalence of Occult Contralateral Foci.

ABSTRACT:

Importance

Standard treatment for patients with medullary thyroid cancer (MTC) consists of total thyroidectomy with central neck dissection, but the rationale for bilateral surgery in patients with unilateral disease on ultrasonography remains unclear.

Objective

To determine the presence of occult contralateral disease (lesions not seen on preoperative ultrasonography) in patients with MTC as a rationale for total thyroidectomy.

Design, setting, and participants

This multi-institutional, retrospective cohort study was conducted from September 1998 to April 2022 in academic medical centers and included patients with MTC who underwent thyroidectomy with preoperative imaging.

Main outcomes and measures

The primary end point was the prevalence of sonographically oc

SUBMITTER: Mao YV 

PROVIDER: S-EPMC10811588 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature