High indirect bilirubin levels as an independent predictor of postoperative myasthenic crisis: a single-center, retrospective study.

ABSTRACT:

Background

Thymectomy is an efficient and standard treatment strategy for patients with myasthenia gravis (MG), postoperative myasthenic crisis (POMC) is the major complication related to thymectomy and has a strongly life-threatening effect. As a biomarker, whether the bilirubin level is a risk factor for MG progression remains unclear. This study aimed to investigate the association between the preoperative bilirubin level and postoperative myasthenic crisis (POMC).

Methods

We analyzed 375 patients with MG who underwent thymectomy at Tangdu Hospital between January 2012 and September 2021. The primary outcome measurement was POMC. The association between POMC and bilirubin level was analyzed by restricted cubic spline (RCS). Indirect bilirubin (IBIL) was divided into two s

SUBMITTER: Sun C 

PROVIDER: S-EPMC10811789 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature