Alterations and correlations in dental plaque microbial communities and metabolome characteristics in patients with caries, periodontitis, and comorbid diseases.

ABSTRACT:

Backgrounds

The pathogenic microorganisms and clinical manifestations of caries and periodontitis are different, caries and periodontitis are usually discussed separately, and the relationship between them is ignored. Clinically, patients prone to dental caries generally have a healthier periodontal status, whereas patients with periodontitis generally have a lower incidence of dental caries. The relationship between dental caries and periodontitis remains unclear.

Objectives

This study aimed to explain the clinical phenomenon of antagonism between dental caries and periodontitis by exploring the ecological chain and bacterial interactions in dental caries, periodontitis, and other comorbid diseases.

Methods

The dental plaque microbiomes of 30 patients with oral disea

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10811826 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature