Prevalence, associated factors, and gene polymorphisms of obesity in Tibetan adults in Qinghai, China.

ABSTRACT:

Objectives

To explore the prevalence and associated factors of obesity in Tibetan adults in Qinghai, China, and to determine the association between the FTO (rs1121980 and rs17817449) and MC4R gene (rs17782313 and rs12970134) polymorphisms with obesity.

Methods

A cross-sectional survey was conducted in 2015 in Qinghai to selected Tibetan adults aged 20 to 80 years. Prevalence of obesity (BMI ≥ 28 kg/m²) and overweight (BMI 24 ~ 27.9 kg/m²) were evaluated. Multivariable logistic models were used to determine the associated factors. Pair-matched subjects of obesity cases and normal-weight controls were selected for the gene polymorphism analyses. Conditional logistic models were used to assess the association between gene polymorphisms with obesity. Addit

SUBMITTER: Wang Y 

PROVIDER: S-EPMC10811834 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature