Long-term follow-up of cats in complete remission after treatment of feline infectious peritonitis with oral GS-441524.

ABSTRACT:

Objectives

Feline infectious peritonitis (FIP), a common disease in cats caused by feline coronavirus (FCoV), is usually fatal once clinical signs appear. Successful treatment of FIP with oral GS-441524 for 84 days was demonstrated recently by this research group. The aim of this study was to evaluate the long-term outcome in these cats.

Methods

A total of 18 successfully treated cats were followed for up to 1 year after treatment initiation (9 months after completion of the antiviral treatment). Follow-up examinations were performed at 12-week intervals, including physical examination, haematology, serum biochemistry, abdominal and thoracic ultrasound, FCoV ribonucleic acid (RNA) loads in blood and faeces by reverse transciptase-quantitative PCR and anti-FCoV antibody titre

SUBMITTER: Zwicklbauer K 

PROVIDER: S-EPMC10811998 | biostudies-literature | 2023 Aug

REPOSITORIES: biostudies-literature