Pegylated-l-asparaginase therapy for feline large cell lymphoma: 82 cases (2017-2020).

ABSTRACT:

Objectives

The present study aimed to investigate pegylated-l-asparaginase monotherapy for feline large cell lymphoma as a potential alternative to palliative corticosteroids treatment in animals whose owners declined cytotoxic chemotherapy.

Methods

A retrospective, descriptive case series of cats treated initially with pegylated-l-asparaginase as a sole therapy for feline large cell lymphoma is reported. The treatment protocol consisted of 12 intramuscular injections of pegylated-l-asparaginase with increasing intervals. If cats were unresponsive to pegylated-l-asparaginase monotherapy, a second-line treatment was initiated. Signalment, origin of lymphoma, staging, treatment, possible adverse events and follow-up data were extracted from the medical records. Responses and s

SUBMITTER: Bik CA 

PROVIDER: S-EPMC10812027 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature