Comparative Bioinformatic Analysis of the Proteomes of Rabbit and Human Sex Chromosomes.

ABSTRACT: Studying proteins associated with sex chromosomes can provide insights into sex-specific proteins. Membrane proteins accessible through the cell surface may serve as excellent targets for diagnostic, therapeutic, or even technological purposes, such as sperm sexing technologies. In this context, proteins encoded by sex chromosomes have the potential to become targets for X- or Y-chromosome-bearing spermatozoa. Due to the limited availability of proteomic studies on rabbit spermatozoa and poorly annotated databases for rabbits compared to humans, a bioinformatic analysis of the available rabbit X chromosome proteome (RX), as well as the human X (HX) and Y (HY) chromosomes proteome, was conducted to identify potential targets that could be accessible from the cell surface and predict which o

SUBMITTER: Pinto-Pinho P 

PROVIDER: S-EPMC10812427 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature