Impact of Multiplex PCR in the Therapeutic Management of Severe Bacterial Pneumonia.

ABSTRACT: Pneumonia is a common and severe illness that requires prompt and effective management. Advanced, rapid, and accurate tools are needed to diagnose patients with severe bacterial pneumonia, and to rapidly select appropriate antimicrobial therapy, which must be initiated within the first few hours of care. Two multiplex molecular tests, Unyvero HPN and FilmArray Pneumonia+ Panel, have been developed using the multiplex polymerase chain reaction (mPCR) technique to rapidly identify pathogens and their main antibiotic resistance mechanisms from patient respiratory specimens. Performance evaluation of these tests showed strong correlations with reference techniques. However, good knowledge of their indications, targets, and limitations is essential. Collaboration with microbiologists is, theref

SUBMITTER: Dessajan J 

PROVIDER: S-EPMC10812737 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature