Treatment-related mortality in children with cancer in low-income and middle-income countries: a systematic review and meta-analysis.

ABSTRACT:

Background

Approximately 90% of children with cancer live in low-income and middle-income countries (LMICs), where 5-year survival is lower than 20%. Treatment-related mortality in high-income countries is approximately 3-5%; however, in LMICs, treatment-related mortality has been reported in up to 45% of children with cancer. This study aimed to systematically explore the burden of treatment-related mortality in children with cancer in LMICs and to explore the association between country income level and treatment-related mortality.

Methods

For this systematic review and meta-analysis we identified articles published between Jan 1, 2010, and June 22, 2021, describing treatment-related mortality in paediatric patients (aged 0-21 years) with cancer in LMICs. We searched PubMe

SUBMITTER: Ehrlich BS 

PROVIDER: S-EPMC10812862 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature