Magnetic Field Intervention Enhances Cellular Migration Rates in Biological Scaffolds.

ABSTRACT: The impact of magnetic fields on cellular function is diverse but can be described at least in part by the radical pair mechanism (RPM), where magnetic field intervention alters reactive oxygen species (ROS) populations and downstream cellular signaling. Here, cellular migration within three-dimensional scaffolds was monitored in an applied oscillating 1.4 MHz radiofrequency (RF) magnetic field with an amplitude of 10 µT and a static 50 µT magnetic field. Given that cellular bioenergetics can be altered based on applied RF magnetic fields, this study focused on a magnetic field configuration that increased cellular respiration. Results suggest that RF accelerated cell clustering and elongation after 1 day, with increased levels of clustering and cellular linkage after 7 days. Cell distribu

SUBMITTER: Vecheck AM 

PROVIDER: S-EPMC10813414 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature