PET/MRI and Novel Targets for Breast Cancer.

ABSTRACT: Breast cancer, with its global prevalence and impact on women's health, necessitates effective early detection and accurate staging for optimal patient outcomes. Traditional imaging modalities such as mammography, ultrasound, and dynamic contrast-enhanced magnetic resonance imaging (MRI) play crucial roles in local-regional assessment, while bone scintigraphy and ¹⁸F-fluorodeoxyglucose positron emission tomography/computed tomography (¹⁸F-FDG PET/CT) aid in evaluating distant metastasis. Despite the proven utility of ¹⁸F-FDG PET/CT in various cancers, its limitations in breast cancer, such as high false-negative rates for small and low-grade tumors, have driven exploration into novel targets for PET radiotracers, including estrogen receptor, human epidermal

SUBMITTER: Chung HW 

PROVIDER: S-EPMC10813582 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature