Use of single nucleotide polymorphisms in the plcR gene for specific identification of Bacillus anthracis.

ABSTRACT: A TaqMan-minor groove binding assay designed around a nonsense mutation in the plcR gene was used to genotype Bacillus anthracis, B. cereus, and B. thuringiensis isolates. The assay differentiated B. anthracis from these genetic near-neighbors and determined that the nonsense mutation is ubiquitous across 89 globally and genetically diverse B. anthracis strains.

SUBMITTER: Easterday WR 

PROVIDER: S-EPMC1081367 | biostudies-literature | 2005 Apr

REPOSITORIES: biostudies-literature