Minimal Clinically Important Difference of Scales Reported in Stroke Trials: A Review.

ABSTRACT: There is a growing awareness of the significance of using minimum clinically important differences (MCIDs) in stroke research. An MCID is the smallest change in an outcome measure that is considered clinically meaningful. This review is the first to provide a comprehensive summary of various scales and patient-reported outcome measures (PROMs) used in stroke research and their MCID values reported in the literature, including a concise overview of the concept of and methods for determining MCIDs in stroke research. Despite the controversies and limitations surrounding the estimation of MCIDs, their importance in modern clinical trials cannot be overstated. Anchor-based and distribution-based methods are recommended for estimating MCIDs, with patient self-evaluation being a crucial componen

SUBMITTER: Mishra B 

PROVIDER: S-EPMC10813687 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature