Pathophysiology to Risk Factor and Therapeutics to Treatment Strategies on Epilepsy.

ABSTRACT: Epilepsy represents a condition in which abnormal neuronal discharges or the hyperexcitability of neurons occur with synchronicity, presenting a significant public health challenge. Prognostic factors, such as etiology, electroencephalogram (EEG) abnormalities, the type and number of seizures before treatment, as well as the initial unsatisfactory effects of medications, are important considerations. Although there are several third-generation antiepileptic drugs currently available, their multiple side effects can negatively affect patient quality of life. The inheritance and etiology of epilepsy are complex, involving multiple underlying genetic and epigenetic mechanisms. Different neurotransmitters play crucial roles in maintaining the normal physiology of different neurons. Dysregulati

SUBMITTER: Boleti APA 

PROVIDER: S-EPMC10813806 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature