Clinical Assessment of Plaque Removal Using a Novel Dentifrice Containing Cellulose Microfibrils.

ABSTRACT: Dentifrice performance in the removal of dental plaque is influenced by the interactions of dentifrice components with tooth surfaces. This randomized controlled clinical study assessed the effectiveness and safety of a novel fluoride dentifrice formulation that included a micro-fibrillated cellulose network with entangled microcrystalline cellulose and silica particles (Protegera^TM), and compared this to a positive control fluoride dentifrice (Crest Cavity Protection™). Whole mouth dental plaque levels in 82 healthy adults were measured after the first supervised use, and following a week of twice daily use at home. Overall, the test dentifrice was at least three times and up to four times more effective in whole-mouth plaque reductions, with a 38.6% reduction on first use, a 3

SUBMITTER: Labib ME 

PROVIDER: S-EPMC10813951 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature