The Smokers Health Multiple ACtions (SMAC-1) Trial: Study Design and Results of the Baseline Round.

ABSTRACT:

Background

Lung cancer screening with low-dose helical computed tomography (LDCT) reduces mortality in high-risk subjects. Cigarette smoking is linked to up to 90% of lung cancer deaths. Even more so, it is a key risk factor for many other cancers and cardiovascular and pulmonary diseases. The Smokers health Multiple ACtions (SMAC-1) trial aimed to demonstrate the feasibility and effectiveness of an integrated program based on the early detection of smoking-related thoraco-cardiovascular diseases in high-risk subjects, combined with primary prevention. A new multi-component screening design was utilized to strengthen the framework on conventional lung cancer screening programs. We report here the study design and the results from our baseline round, focusing on oncological findings

SUBMITTER: Antonicelli A 

PROVIDER: S-EPMC10814085 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature