Tumor Response on Diagnostic Imaging after Proton Beam Therapy for Hepatocellular Carcinoma.

ABSTRACT:

Background

Follow-up after treatment for hepatocellular carcinoma (HCC) can be mostly performed using dynamic CT or MRI, but there is no common evaluation method after radiation therapy. The purpose of this study is to examine factors involved in tumor reduction and local recurrence in patients with HCC treated with proton beam therapy (PBT) and to evaluate HCC shrinkage after PBT.

Methods

Cases with only one irradiated lesion or those with two lesions irradiated simultaneously were included in this study. Pre- and post-treatment lesions were evaluated using Response Evaluation Criteria in Solid Tumors (RECIST) by measuring the largest diameter.

Results

The 6-, 12-, and 24-month CR + PR rates after PBT were 33.1%, 57.5%, and 76.9%, respectively, and the reduction rate

SUBMITTER: Niitsu H 

PROVIDER: S-EPMC10814092 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature