B Cells and Double-Negative B Cells (CD27^-IgD^-) Are Related to Acute Pancreatitis Severity.

ABSTRACT: Acute pancreatitis (AP) is an increasingly frequent disease in which inflammation plays a crucial role. Fifty patients hospitalized with AP were included and peripheral blood samples were analyzed for B and T cell subpopulations at the time of hospitalization and 48 h after diagnosis. The Bedside Index of Severity in Acute Pancreatitis (BISAP) and length of hospital stay were also recorded. A healthy control (HC) group of 15 outpatients was included. AP patients showed higher neutrophil/lymphocyte (N/L) ratios and higher percentages of B cells than the HC group. The total B cell percentages were higher in patients with moderate/severe AP than in patients with mild AP. The percentages of B cells as well as the percentages of the CD27^-IgD^- B cell subset decreased from a

SUBMITTER: Malheiro F 

PROVIDER: S-EPMC10814478 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature