A New Method to Evaluate Lower Esophageal Distension Capacity in Eosinophilic Esophagitis by Using Functional Lumen Imaging Probe (EndoFLIP™).

ABSTRACT: Endoluminal functional lumen impedance planimetry (EndoFLIP^TM) has become the gold standard to evaluate esophageal distensibility, although the study itself and its analysis present challenges. We propose here a new method to assess lower esophageal distension capacity that overcomes several limitations of prior approaches, including incomplete and corrupted EndoFLIP^TM recordings. Esophageal distension capacity was evaluated with a 16-channel EndoFLIP^TM in 10 controls and 14 patients with eosinophilic esophagitis (EoE). Controls were evaluated once. EoE patients were evaluated at baseline and after at least six weeks of treatment with orodispersible budesonide tablets, 1 mg bd. Balloon volumes were increased by 5 mL stepwise, either reaching a maximum volum

SUBMITTER: Casabona-Frances S 

PROVIDER: S-EPMC10814586 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature