MicroAnnot: A Dedicated Workflow for Accurate Microsporidian Genome Annotation.

ABSTRACT: With nearly 1700 species, Microsporidia represent a group of obligate intracellular eukaryotes with veterinary, economic and medical impacts. To help understand the biological functions of these microorganisms, complete genome sequencing is routinely used. Nevertheless, the proper prediction of their gene catalogue is challenging due to their taxon-specific evolutionary features. As innovative genome annotation strategies are needed to obtain a representative snapshot of the overall lifestyle of these parasites, the MicroAnnot tool, a dedicated workflow for microsporidian sequence annotation using data from curated databases of accurately annotated microsporidian genes, has been developed. Furthermore, specific modules have been implemented to perform small gene (<300 bp) and transposable

SUBMITTER: Tournayre J 

PROVIDER: S-EPMC10815200 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature