Exploring the Therapeutic Significance of microRNAs and lncRNAs in Kidney Diseases.

ABSTRACT: MicroRNAs (miRNAs) and long non-coding RNAs (lncRNAs) are two crucial classes of transcripts that belong to the major group of non-coding RNAs (ncRNAs). These RNA molecules have significant influence over diverse molecular processes due to their crucial role as regulators of gene expression. However, the dysregulated expression of these ncRNAs constitutes a fundamental factor in the etiology and progression of a wide variety of multifaceted human diseases, including kidney diseases. In this context, over the past years, compelling evidence has shown that miRNAs and lncRNAs could be prospective targets for the development of next-generation drugs against kidney diseases as they participate in a number of disease-associated processes, such as podocyte and nephron death, renal fibrosis, infla

SUBMITTER: Bravo-Vazquez LA 

PROVIDER: S-EPMC10815231 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature