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Navigating the Cytokine Seas: Targeting Cytokine Signaling Pathways in Cancer Therapy.

ABSTRACT: Cancer remains one of the leading causes of morbidity and mortality worldwide, necessitating continuous efforts to develop effective therapeutic strategies. Over the years, advancements in our understanding of the complex interplay between the immune system and cancer cells have led to the development of immunotherapies that revolutionize cancer treatment. Cytokines, as key regulators of the immune response, are involved in both the initiation and progression of cancer by affecting inflammation and manipulating multiple intracellular signaling pathways that regulate cell growth, proliferation, and migration. Cytokines, as key regulators of inflammation, have emerged as promising candidates for cancer therapy. This review article aims to provide an overview of the significance of cytokines in cancer development and therapy by highlighting the importance of targeting cytokine signaling pathways as a potential therapeutic approach.

SUBMITTER: Stanilov N

PROVIDER: S-EPMC10815616 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature

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Navigating the Cytokine Seas: Targeting Cytokine Signaling Pathways in Cancer Therapy.

Stanilov Noyko N Velikova Tsvetelina T Stanilova Spaska S

International journal of molecular sciences 20240113 2

Cancer remains one of the leading causes of morbidity and mortality worldwide, necessitating continuous efforts to develop effective therapeutic strategies. Over the years, advancements in our understanding of the complex interplay between the immune system and cancer cells have led to the development of immunotherapies that revolutionize cancer treatment. Cytokines, as key regulators of the immune response, are involved in both the initiation and progression of cancer by affecting inflammation ...[more]

PMID: 38256080

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