Fabrication of Alginate/Ozoile Gel Microspheres by Electrospray Process.

ABSTRACT: Natural polymers, such as alginate and chitosan, are widely exploited for drug delivery applications due to their biocompatibility, low toxicity, and sustainable sourcing. In this study, pH-responsive gel microspheres were fabricated from an alginate/Ozoile emulsion. Ozoile (Stable Ozonides) is a biological inducer, derived from olive oil, which stimulates the endogenous defense system by promoting the repair of tissue damage and restoration of proper physiology through the regulation of gene transcription. Here, the versatile and cost-effective electrospray technique without the use of organic solvents was used to fabricate alginate/Ozoile microspheres with high throughput. The process parameters (voltage, flow rate, and needle gauge) were optimized to obtain microspheres with good spheri

SUBMITTER: Ciarleglio G 

PROVIDER: S-EPMC10815707 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature