The Influence of Graphene Oxide-Fe₃O₄ Differently Conjugated with 10-Hydroxycampthotecin and a Rotating Magnetic Field on Adenocarcinoma Cells.

ABSTRACT: Nanoparticles (e.g., graphene oxide, graphene oxide-Fe₃O₄ nanocomposite or hexagonal boron nitride) loaded with anti-cancer drugs and targeted at cancerous cells allowed researchers to determine the most effective in vitro conditions for anticancer treatment. For this reason, the main propose of the present study was to determine the effect of graphene oxide (GO) with iron oxide (Fe₃O₄) nanoparticles (GO-Fe₃O₄) covalently (c-GO-Fe₃O₄-HCPT) and non-covalently (nc-GO-Fe₃O₄-HCPT) conjugated with hydroxycamptothecin (HCPT) in the presence of a rotating magnetic field (RMF) on relative cell viability using the MCF-7 breast cancer cell line. The obtained GO-Fe₃O₄ na

SUBMITTER: Jedrzejczak-Silicka M 

PROVIDER: S-EPMC10816047 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature