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Decongestion in Acute Heart Failure-Time to Rethink and Standardize Current Clinical Practice?


ABSTRACT: Most episodes of acute heart failure (AHF) are characterized by increasing signs and symptoms of congestion, manifested by edema, pleura effusion and/or ascites. Immediately and repeatedly administered intravenous (IV) loop diuretics currently represent the mainstay of initial therapy aiming to achieve adequate diuresis/natriuresis and euvolemia. Despite these efforts, a significant proportion of patients have residual congestion at discharge, which is associated with a poor prognosis. Therefore, a standardized approach is needed. The door to diuretic time should not exceed 60 min. As a general rule, the starting IV dose is 20-40 mg furosemide equivalents in loop diuretic naïve patients or double the preexisting oral home dose to be administered via IV. Monitoring responses within the foll

SUBMITTER: Bilgeri V 

PROVIDER: S-EPMC10816514 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature