Kick-Starting Wound Healing: A Review of Pro-Healing Drugs.

ABSTRACT: Cutaneous wound healing consists of four stages: hemostasis, inflammation, proliferation/repair, and remodeling. While healthy wounds normally heal in four to six weeks, a variety of underlying medical conditions can impair the progression through the stages of wound healing, resulting in the development of chronic, non-healing wounds. Great progress has been made in developing wound dressings and improving surgical techniques, yet challenges remain in finding effective therapeutics that directly promote healing. This review examines the current understanding of the pro-healing effects of targeted pharmaceuticals, re-purposed drugs, natural products, and cell-based therapies on the various cell types present in normal and chronic wounds. Overall, despite several promising studies, there re

SUBMITTER: Patenall BL 

PROVIDER: S-EPMC10816820 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature