Comparison of Combined Parenteral and Oral Hormonal Contraceptives: A Systematic Review and Meta-Analysis of Randomized Trials.

ABSTRACT:

Background

Delivering contraceptive hormones through a transdermal patch or a vaginal ring might have advantages over the traditional oral route.

Objectives

To compare the effectiveness, compliance, and side effect profile of oral and parenteral drug administration methods.

Methods

We performed a systematic literature search in four medical databases-MEDLINE (via PubMed), Cochrane Library (CENTRAL), Embase, and Scopus-from inception to 20 November 2022. Randomized controlled trials assessing the efficacy, compliance, and adverse event profile of combined parenteral and oral hormonal contraceptives were included.

Results

Our systematic search provided 3952 records; after duplicate removal, we screened 2707 duplicate-free records. A total of 13 eligible studies w

SUBMITTER: Vlesko G 

PROVIDER: S-EPMC10816843 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature