Antifungal Resistance and Genotyping of Clinical Candida parapsilosis Complex in Japan.

ABSTRACT: Non-albicans Candida infections have recently gained worldwide attention due to their intrinsic resistance to different antifungal agents and the limited therapeutic options for treating them. Although the Candida parapsilosis complex is reported to be the second or third most prevalent Candida spp., little information is available on the prevalence of antifungal resistance along with genotyping of the C. parapsilosis complex. In this study, we aimed to evaluate the prevalence of antifungal resistance, the genetic basis of such resistance, and the genotyping of C. parapsilosis complex isolates that were recovered from hospitalized patients in Japan from 2005 to 2019. Our results indicated that, with the exception of one single C. metapsilosis isola

SUBMITTER: Khalifa HO 

PROVIDER: S-EPMC10816931 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature