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Association between ELMO1 gene polymorphisms and diabetic kidney disease: A systematic review and meta-analysis.


ABSTRACT:

Background

Previous research has suggested that the ELMO1 gene may play a role in the development of diabetic kidney disease. Diabetic kidney disease (DKD) is a serious complication of diabetes and the leading cause of chronic kidney disease and end-stage renal disease (ESRD).

Objective and rationale

This study aim was to systematically review and explore the association between ELMO1 gene polymorphisms and diabetic kidney disease. A comprehensive systematic review provides a clear conclusion and high-level evidence for the association between ELMO1 gene and DKD for future application in personalized medicine.

Methods

A comprehensive search of electronic databases, per PRISMA instructions, was conducted in Scopus, EMBASE, Web of Science, and PubMed databases from 1980

SUBMITTER: Azarboo A 

PROVIDER: S-EPMC10817128 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature