Antimicrobial Oleogel Containing Sustainably Prepared Silver-Based Nanomaterials for Topical Application.

ABSTRACT: Oleogels containing silica-silver-based nanomaterials were prepared to be used as potential antimicrobial treatment for preventing and curing skin infections. Fumed silica was used as a bifunctional excipient able to offer support to silver-based nanoparticle growth and act as a gelling agent for oleogel formulation. First, silica-silver composites were prepared following a sustainable method by contact of fumed silica and silver nitrate in the presence of ethanol and successive UV irradiation. The composites were characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), ATR FT-IR spectroscopy and UV-Vis spectrophotometry. The presence of 8-20 nm spherical nanoparticles, in addition to the silica aggregates and AgNO₃ crystals, was detected. The

SUBMITTER: Ambrogi V 

PROVIDER: S-EPMC10817458 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature