When Sex Matters: Differences in the Central Nervous System as Imaged by OCT through the Retina.

ABSTRACT:

Background

Retinal texture has gained momentum as a source of biomarkers of neurodegeneration, as it is sensitive to subtle differences in the central nervous system from texture analysis of the neuroretina. Sex differences in the retina structure, as detected by layer thickness measurements from optical coherence tomography (OCT) data, have been discussed in the literature. However, the effect of sex on retinal interocular differences in healthy adults has been overlooked and remains largely unreported.

Methods

We computed mean value fundus images for the neuroretina layers as imaged by OCT of healthy individuals. Texture metrics were obtained from these images to assess whether women and men have the same retina texture characteristics in both eyes. Texture features were t

SUBMITTER: Nunes A 

PROVIDER: S-EPMC10817590 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature