Preeclampsia and Long-term Kidney Outcomes: An Observational Cohort Study.

ABSTRACT:

Rationale & objective

Preeclampsia is a pregnancy-related complication characterized by acute hypertension and end-organ dysfunction. We evaluated the long-term association between preeclampsia and the risk of developing chronic hypertension and kidney disease.

Study design

Observational cohort study.

Setting & participants

27,800 adults with deliveries in the Geisinger Health System between 1996 and 2019.

Exposure

Preeclampsia.

Outcome

Hypertension, reduced estimated glomerular filtration rate (eGFR)<60mL/min/1.73m²), and albuminuria>300mg/g.

Analytical approach

Propensity-score matching and Cox proportional hazards models to evaluate the association between preeclampsia and incident hypertension, reduced eGFR, and albuminuria.

Resu

SUBMITTER: Srialluri N 

PROVIDER: S-EPMC10818021 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature