Non-Woven Fibrous Polylactic Acid/Hydroxyapatite Nanocomposites Obtained via Solution Blow Spinning: Morphology, Thermal and Mechanical Behavior.

ABSTRACT: Polylactic acid (PLA) is widely used in tissue engineering and other biomedical applications. PLA can be modified with appropriate biocompatible ceramic materials since this would allow tailoring the mechanical properties of the tissues to be engineered. In this study, PLA-based non-woven fibrillar nanocomposites containing nanoparticles of hydroxyapatite (HA), a bioceramic commonly used in bone tissue engineering, were prepared via solution blow spinning (SBS). The compositions of the final materials were selected to study the influence of HA concentration on the structure, morphology, and thermal and mechanical properties. The resulting materials were highly porous and mainly constituted fibers. FTIR analysis did not reveal any specific interactions. The diameters of the fibers varied ve

SUBMITTER: Gonzalez-Benito J 

PROVIDER: S-EPMC10818388 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature