Synthesis of Indenones via Persulfate Promoted Radical Alkylation/Cyclization of Biaryl Ynones with 1,4-Dihydropyridines.

ABSTRACT: The oxidative radical cascade cyclization of alkynes has emerged as a versatile strategy for the efficient construction of diverse structural units and complex molecules in organic chemistry. This work reports an alkyl radical initiated 5-exo-trig cyclization of biaryl ynones with 1,4-dihydropyridines to selectively synthesize indenones.

SUBMITTER: Wang W 

PROVIDER: S-EPMC10818456 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature