Ontology highlight
ABSTRACT:
SUBMITTER: Wang S
PROVIDER: S-EPMC10818657 | biostudies-literature | 2023 Dec
REPOSITORIES: biostudies-literature
Wang Shixia S Guirakhoo Farshad F Periasamy Sivakumar S Ryan Valorie V Wiggins Jonathan J Subramani Chandru C Thibodeaux Brett B Sahni Jaya J Hellerstein Michael M Kuzmina Natalia A NA Bukreyev Alexander A Dodart Jean-Cosme JC Rumyantsev Alexander A
Vaccines 20231229 1
Antibodies provide critical protective immunity against COVID-19, and the Fc-mediated effector functions and mucosal antibodies also contribute to the protection. To expand the characterization of humoral immunity stimulated by subunit protein-peptide COVID-19 vaccine UB-612, preclinical studies in non-human primates were undertaken to investigate mucosal secretion and the effector functionality of vaccine-induced antibodies in antibody-dependent monocyte phagocytosis (ADMP) and antibody-depende ...[more]