Exploring the Effectiveness of Biological Therapy in Patients with Psoriasis: Body Image and Quality of Life.

ABSTRACT: Background and Objectives: Psoriasis is a chronic, long-term, incurable skin inflammatory disease characterized by the excessive proliferation of epidermal keratinocytes, dilation of blood vessels, thickening of the skin, and the formation of visible red patches of variable sizes. The impact on patients differs with the severity of the disease, leading to physiological discomfort and psychological distress, which significantly affect the quality of life. The etiology of psoriasis is not completely clear, but immune cells, including type 1 and type 17 cytokine-producing cells modulated by regulatory T cells (Tregs), play a critical role in driving the disease pathogenesis. With the ability to specifically target inflammatory markers, biologics can efficiently inhibit the spread of in

SUBMITTER: Wu CL 

PROVIDER: S-EPMC10819774 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature