Direct Impact of the Air on Mutant Cells for Mutagenicity Assessments in Urban Environments.

ABSTRACT:

Background

Urban air pollution is recognized as a critical problem for public health and is classified as a carcinogen for humans. A great number of studies have focused on the monitoring of urban air mutagenicity. One of the best-known and applied methods for assessing mutagenicity is the Ames test, a bacterial reverse mutation test. The classic protocol for assessing air mutagenicity involves the concentration of particulate matter (PM) on filters and subsequent extraction using organic solvents. This work aimed to develop a method for the evaluation of air mutagenicity directly impacted by air on microbial plates already containing an Ames' microbial sensor.

Methods

A specific six-month sampling campaign was carried out in Turin in a period with high air pollution. Sample

SUBMITTER: Caredda C 

PROVIDER: S-EPMC10820087 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature