Vaccines to Treat Substance Use Disorders: Current Status and Future Directions.

ABSTRACT: Addiction, particularly in relation to psychostimulants and opioids, persists as a global health crisis with profound social and economic ramifications. Traditional interventions, including medications and behavioral therapies, often encounter limited success due to the chronic and relapsing nature of addictive disorders. Consequently, there is significant interest in the development of innovative therapeutics to counteract the effects of abused substances. In recent years, vaccines have emerged as a novel and promising strategy to tackle addiction. Anti-drug vaccines are designed to stimulate the immune system to produce antibodies that bind to addictive compounds, such as nicotine, cocaine, morphine, methamphetamine, and heroin. These antibodies effectively neutralize the target molecule

SUBMITTER: Lu T 

PROVIDER: S-EPMC10820210 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature