Evolution of spontaneous portosystemic shunts over time and following aetiological intervention in patients with cirrhosis.

ABSTRACT:

Background & aims

Spontaneous portosystemic shunts (SPSS) develop frequently in cirrhosis. Changes over time and the effect of aetiological interventions on SPSS are unknown, so we aimed to explore the effect of these variables on SPSS evolution.

Methods

Patients with cirrhosis from the Baveno VI-SPSS cohort were selected provided a follow-up abdominal CT or MRI scan was available. Clinical and laboratory data were collected at baseline and follow-up. Imaging tests were reviewed to evaluate changes in the presence and size of SPSS (large (L)-SPSS was ≥8 mm) over time. Regarding alcohol- or HCV-related cirrhosis, two populations were defined: cured patients (abstinent from alcohol or successful HCV therapy), and non-cured patients.

Results

A total of 617 patients were

SUBMITTER: Vidal-Gonzalez J 

PROVIDER: S-EPMC10820312 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature