Efficient Chlorostannate Modification of Magnetite Nanoparticles for Their Biofunctionalization.

ABSTRACT: Magnetite nanoparticles (MNPs) are highly favored materials for a wide range of applications, from smart composite materials and biosensors to targeted drug delivery. These multifunctional applications typically require the biofunctional coating of MNPs that involves various conjugation techniques to form stable MNP-biomolecule complexes. In this study, a cost-effective method is developed for the chlorostannate modification of MNP surfaces that provides efficient one-step conjugation with biomolecules. The proposed method was validated using MNPs obtained via an optimized co-precipitation technique that included the use of degassed water, argon atmosphere, and the pre-filtering of FeCl₂ and FeCl₃ solutions followed by MNP surface modification using stannous chloride.

SUBMITTER: Zolotova MO 

PROVIDER: S-EPMC10820483 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature