Magnesium Hydroxide as a Versatile Nanofiller for 3D-Printed PLA Bone Scaffolds.

ABSTRACT: Polylactic acid (PLA) has attracted much attention in bone tissue engineering due to its good biocompatibility and processability, but it still faces problems such as a slow degradation rate, acidic degradation product, weak biomineralization ability, and poor cell response, which limits its wider application in developing bone scaffolds. In this study, Mg(OH)₂ nanoparticles were employed as a versatile nanofiller for developing PLA/Mg(OH)₂ composite bone scaffolds using fused deposition modeling (FDM) 3D printing technology, and its mechanical, degradation, and biological properties were evaluated. The mechanical tests revealed that a 5 wt% addition of Mg(OH)₂ improved the tensile and compressive strengths of the PLA scaffold by 20.50% and 63.97%, respecti

SUBMITTER: Guo W 

PROVIDER: S-EPMC10820754 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature