Associations among gene polymorphisms, crestal bone loss, and bone mineral density in patients receiving dental implants.

ABSTRACT:

Objectives

Interleukin 1 (IL-1) and interleukin 6 (IL-6) gene polymorphisms have been suggested to be responsible for diminished bone mineral density (BMD) and high crestal bone loss (CBL) in some individuals. However, the effects of systemic BMD on variations in peri-implant CBL are unclear. Hence, this study was aimed at investigating the association of IL-1 and IL-6 gene polymorphisms with systemic BMD and CBL around dental implants.

Methods

A total of 190 participants undergoing dental implantation in the mandibular posterior region were selected according to predetermined selection criteria and divided into a normal BMD group (NBD, 93 participants, T-score ≥ -1) and low BMD group (LBD, including both osteoporosis and osteopenia, 97 participants, T-score < -1 standard de

SUBMITTER: Agrawal KK 

PROVIDER: S-EPMC10820795 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature