Bioprospection of Tenellins Produced by the Entomopathogenic Fungus Beauveria neobassiana.

ABSTRACT: Fungi are known as prolific producers of bioactive secondary metabolites with applications across various fields, including infectious diseases, as well as in biological control. However, some of the well-known species are still underexplored. Our current study evaluated the production of secondary metabolites by the entomopathogenic fungus Beauveria neobassiana from Thailand. The fermentation of this fungus in a liquid medium, followed by preparative high-performance liquid chromatography (HPLC) purification, resulted in the isolation of a new tenellin congener, namely pretenellin C (1), together with five known derivatives (2-6). Their chemical structures were elucidated by 1D and 2D nuclear magnetic resonance (NMR) spectroscopy in combination with high-resolu

SUBMITTER: Toshe R 

PROVIDER: S-EPMC10821025 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature