A Composite Score for Predicting Vertical Transmission of Hepatitis C: A Multicenter Study.

ABSTRACT:

Background

Prevention of the vertical transmission of the hepatitis C virus (HCV) presents an obstetric challenge. There are no approved antiviral medications for the treatment or prevention of HCV for pregnant patients.

Objective

We aimed to create a composite score to accurately identify a population of pregnant patients with HCV who have high potential for vertical transmission.

Study design

In a retrospective, multicenter cohort study, we identified pregnant patients with hepatitis C with linked data to their infants who have had HCV RNA or HCV antibody testing. Demographic data, including age and race/ethnicity, as well as clinical and laboratory data, including tobacco/alcohol use, infections, liver function tests, the HCV RNA titer, HCV antibody, HCV genotype,

SUBMITTER: Wasuwanich P 

PROVIDER: S-EPMC10821345 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature