Exploring the Genomic Dynamics of the Monkeypox Epidemic in Paraguay.

ABSTRACT: In recent months, Paraguay has been grappled with a notable monkeypox outbreak, straining its healthcare infrastructure. The sudden spike in cases underlines the imperative need for a comprehensive understanding of the virus's dynamics, enabling the formulation of robust containment measures. To address this challenge, our team joined forces with the Central Public Health Laboratory of Asunción and the Pan-American Health Organization. Through this collaboration, we employed portable whole-genome sequencing combined with phylodynamic analysis to examine the MPXV strains circulating in Paraguay. Our genomic monitoring approach has produced the first 30 whole-genome sequences from Paraguay, all of which were identified under lineage IIb. Interestingly, our data suggest that the origin of the

SUBMITTER: Vazquez C 

PROVIDER: S-EPMC10821367 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature