A Significant Association between Type 1 Diabetes and Helicobacter pylori Infection: A Meta-Analysis Study.

ABSTRACT: Background and Objectives: Type 1 diabetes mellitus (T1DM) is a chronic and serious condition that is characterized by inadequate pancreatic-β-cells' insulin production. The connection between T1DM and Helicobacter pylori infection remains uncertain. This study aimed to conduct a systematic meta-analysis to examine the association between H. pylori infection, hemoglobin A1c levels, and the development of T1DM. Materials and Methods: The initial search identified 451 articles on the association between H. pylori infection and T1DM. Among them, 12 articles had 2797 participants who met the inclusion criteria for an advanced meta-analysis. Results: A significant association was observed between H. pylori infection and T1DM (OR 1.77, 95% CI 1.47

SUBMITTER: Chua WK 

PROVIDER: S-EPMC10821400 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature